Using Unisom and B6 to Stop Nausea During Pregnancy

If you’re pregnant and experiencing nausea and vomiting, you’re not alone. These symptoms are common during pregnancy, affecting up to 80% of women.

Fortunately, there are several treatments available, including the combination of Unisom and B6 for nausea.

What is Unisom and B6?


Unisom is an over-the-counter sleep aid that contains the active ingredient doxylamine succinate. When taken in combination with vitamin B6, it may help relieve nausea and vomiting during pregnancy.

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that is found in many foods, including meat, poultry, fish, and some fruits and vegetables. It plays an important role in the development of the nervous system and the production of red blood cells.

How does Unisom and B6 work?

The exact mechanism of action of Unisom and B6 in managing nausea during pregnancy is not fully understood. However, it is thought that Unisom works by blocking histamine receptors in the brain, which can reduce feelings of nausea and promote sleepiness.

Vitamin B6, on the other hand, may help by reducing inflammation and regulating the neurotransmitters that control nausea and vomiting.

Unisom and B6 Dosage

B6 and Unisom are typically taken together, with B6 being taken during the day and Unisom being taken at night. The recommended dosage of B6 is 25 milligrams (mg) three times a day, while the recommended dosage of Unisom is 25 mg at bedtime.

It’s important to note that while Unisom and B6 are considered safe for use during pregnancy, it’s always best to talk to your healthcare provider before taking any medication or supplement. They can help determine the appropriate dosage for you and ensure that there are no potential interactions with any other medications you may be taking.

Are there any side effects of Vitamin B6 and Unisom?

While Vitamin B6 and Unisom are generally considered safe, there are some potential side effects that you should be aware of. The most common side effect of Unisom is drowsiness, which is why it is typically taken at bedtime. Other potential side effects include dry mouth, blurred vision, and constipation.

B6 is generally well-tolerated, but some people may experience nausea, vomiting, or diarrhoea at high doses. In rare cases, high doses of B6 can cause nerve damage, so it’s important to stick to the recommended dosage.

What are some alternatives to Unisom and B6 for Nausea?


If you prefer not to take medication or are looking for alternative treatments, there are several options available for managing nausea and vomiting during pregnancy. Some of these include:

  • Eating small, frequent meals throughout the day to keep your blood sugar levels stable
  • Drinking plenty of fluids, such as water or ginger tea, to stay hydrated
  • Avoiding triggers that can make nausea worse, such as strong smells or greasy foods
  • Trying acupressure, which involves applying pressure to specific points on the body to relieve symptoms
  • Using aromatherapy, such as inhaling peppermint oil or lavender oil, to promote relaxation and reduce nausea


Unisom and B6 can be effective and safe treatment for managing nausea and vomiting during pregnancy. However, it’s important to talk to your healthcare provider before taking any medication or supplement and to follow the recommended dosage.

If you prefer not to take medication, there are several alternative treatments available that may help relieve your symptoms. Whatever treatment you choose, remember that nausea and vomiting during pregnancy are common and usually resolve on their own by the end of the first trimester.

However, in some cases, they can persist throughout the pregnancy, so it’s important to seek medical attention if you are experiencing severe symptoms or if you are unable to keep food or fluids down.

In addition to managing your symptoms, it’s also important to take care of your overall health during pregnancy. This includes getting regular prenatal care, eating a balanced diet, staying active, and getting enough rest. By taking care of yourself and managing your symptoms, you can have a healthy and comfortable pregnancy.